Advancing Safe Medication Practice

Medication safety intelligence for everyone —
IntractMD™

The first AI-driven medication risk platform that analyzes prescriptions, OTC drugs, supplements, foods, and cumulative polypharmacy as a single patient-specific risk profile for pharmacists, health plans, and care management teams.

Try IntractMD Free → For Health Plans
1.5M
ED visits from ADEs each year
34.5%
of ADE ED visits are adults 65+
124,750
Drug pairs in pre-computed cache
What is IntractMD?
IntractMD for the patient, care giver, and the health insurance provider

Grounded in authoritative data sources

FDA Drug Labels
NLM RxNorm
MedlinePlus
Claude AI (Anthropic)
Patent Pending
About Resolve Medical

Bridging the gap between
complexity and clarity

Resolve Medical is a healthcare technology company dedicated to making clinical-grade medication safety tools accessible to everyone — not just specialists with access to expensive databases and EHR systems.

IntractMD addresses one of the most preventable causes of patient harm: unrecognized drug interactions and supplement risks. Adverse drug events cause roughly 1.5 million emergency department visits and 500,000 hospitalizations in the United States each year, and about $3.5 billion in excess medical costs. Older adults carry the heaviest share — 34.5% of ADE-related emergency visits involve adults 65 and over, and 43.6% of those visits end in a hospital admission. An ADE that is already present when a patient arrives at the hospital carries a mean cost of roughly $18,800 in current dollars.

We built IntractMD as a three-surface platform: a patient self-service app, a proactive supplement screening engine for health plans, and a structured clinical workflow for case managers and MTM pharmacists — all running on the same patent-pending scoring engine grounded in FDA data. Pharmacy chains can leverage the toolset to substantially increase the delivery of a reimbursed Comprehensive Medication Review (CMR) to their customers, generating meaningful incremental revenue.

Mission
Make medication safety intelligence accessible to every patient, caregiver, and clinician — regardless of access to specialized systems.
Approach
AI grounded in authoritative FDA data — not standalone guesswork. Every analysis is anchored to official drug labels before Claude AI reasons across them.
Who We Serve
Patients managing chronic conditions, Medicare Advantage health plans, PBMs, hospital MTM programs, retail pharmacy chains, and independent pharmacists.
IntractMD™ Capabilities

Three surfaces. One engine.

IntractMD is a polypharmacy risk platform deployed across three specialized surfaces — patient-facing, institutional proactive screening, and clinical case management — all powered by the same 124,750-pair drug interaction cache and patent-pending scoring methodology.

Patient App — intractmd.com
Self-service drug interaction checker. Patients enter medications, supplements, and foods and receive a plain-language risk report in seconds. Free, no account required, bilingual English and Spanish.
Patient-Facing · Free
Proactive Engine — Supplement & Food Screening
Given a member's medication list, the system identifies every supplement and food they should avoid — before an adverse event occurs. Results in under 200ms from a pre-computed 1,000-drug profile cache. Novel directional inversion query method (patent pending).
Institutional · PMPM Licensed
Clinical Workflow — Case Manager Tool
A structured 6-step institutional workflow combining DDI analysis, 28-factor polypharmacy risk stratification, and confidence-tiered patient outreach generation — email, SMS, and case manager call script — where language automatically shifts based on whether findings are confirmed, computed, or predictive.
MTM · Health Plan · PMPM Licensed
For Health Plans & PBMs

Reduce ADEs. Get ahead of the 2027 Star measures.

IntractMD is licensed to health plans and PBMs on a per-member-per-month basis, applicable to all members, but especially your polypharmacy-eligible population (members 50+ on 5+ medications). A free 60-day pilot is hosted by Resolve Medical. Simply add an IntractMD link to your user portal, and then validate the clinical value before any commitment.

The Clinical Workflow tool generates ready-to-send patient outreach in three formats (email, SMS, call script), with language automatically calibrated to the confidence tier of each finding.

CMS has restored the medication therapy management comprehensive medication review measure to scoring beginning with measurement year 2027, with expanded member eligibility. The three Part D adherence measures are now risk-adjusted for sociodemographic status and are temporarily single-weighted for MY2026 before returning to triple weight. Plans that stand up a medication review workflow during 2026 are scored on it in 2027 — and the Clinical Workflow surface is built for exactly that window.

Three billing models available to fit your contracting preference.

PMPM Licensing — Contact for Pricing

IntractMD is licensed to health plans and PBMs on a per-member-per-month basis, structured to your eligible polypharmacy population and contracting preference. Contact us to discuss a free 60-day pilot and receive a custom pricing proposal.

$18,800
Mean cost of an ADE hospitalization present on admission (AHRQ HCUP, 2014 data in 2026 dollars)
500,000
Annual ADE-related hospitalizations in the US
43.6%
of ADE emergency visits by adults 65+ end in hospital admission (CDC)
46–335%
Higher ADE rates in Medicare vs. commercially insured populations (AHRQ HCUP)
~60%
of ADE emergency visits in adults 65+ involve anticoagulants, diabetes agents, or opioids (CDC)
Request Pilot Information → info@resolve.med

or call 216-509-0672

The IntractMD Risk Score

One number that summarizes
your medication risk

The IntractMD CPRS (Composite Polypharmacy Risk Score) is a composite AI-generated clinical risk index (0–100) that synthesizes 8 pharmacological dimensions simultaneously across your full medication regimen — bleeding risk, cardiac risk, CNS depression, serotonin syndrome, NTI conflict, renal/hepatic impact, CYP450, and pharmacodynamic risk.

It is a clinical decision support signal — not a validated clinical instrument. Always consult a licensed pharmacist or physician before making any medication decision.

0 – 20
Minimal
No significant risks identified
21 – 40
Low
Minor interactions, routine monitoring
41 – 60
Moderate
Active monitoring needed
61 – 80
High
Consider regimen modification
81 – 100
Critical
Urgent clinical review warranted
Newsroom

News & Announcements

Press Release July 28, 2026 Download PDF ↓

Resolve Medical, LLC Launches AI-Driven Platform That Screens Supplements and Foods Against a Patient’s Full Medication List

IntractMD™ gives patients, health plans, and pharmacists one scored view of interaction risk — including the supplements that never appear in claims data. No-cost pilots open now.

CLEVELAND, Ohio — July 28, 2026 — Resolve Medical, LLC today launched IntractMD™, an AI-powered medication interaction platform that screens a patient’s prescriptions together with the dietary supplements, vitamins, and foods they take — a category of risk largely invisible to claims data and electronic health records.

Adverse drug events cause roughly 1.5 million emergency department visits and 500,000 hospitalizations in the United States each year, at an estimated $3.5 billion in excess medical costs. Older adults carry the heaviest share: 34.5% of those emergency visits involve adults 65 and over, and 43.6% of them end in a hospital admission. Supplement use is widespread in exactly that group — roughly 85% of adults over 50 take at least one — yet FDA-cited estimates suggest up to 70% never tell a healthcare provider.

“A pharmacist can see every prescription a patient fills at their counter and still may miss other meds filled elsewhere, or supplements and foods that potentially interfere with the efficacy of the prescription being filled,” said Tom Lash, Founder of Resolve Medical. “That information isn’t in any claims feed or medication list. IntractMD asks for it directly, scores the whole regimen, and gives the patient and provider something they can actually read and act on. This data is invaluable for healthcare providers, insurers, and pharmacists, especially for their polypharmacy patients or members.”
The platform does three things in a single query:
  • Screens drug–drug, drug–supplement, and drug–food interactions together, with no account, login, or installation required
  • Returns a Composite Polypharmacy Risk Score (CPRS) across eight clinical dimensions, including bleeding, cardiac, serotonin, narrow-therapeutic-index, CNS, CYP450, renal/hepatic, and pharmacodynamic risk
  • Inverts the question for proactive use: enter a medication list and receive the supplements and foods to avoid, before anything new is introduced

IntractMD draws on a pre-computed database of 124,750 drug-pair analyses covering the 500 most-prescribed medications in the United States and produces output in both English and Spanish. The platform is the subject of a U.S. provisional patent application filed in June 2026.

No-cost pilots now open

Resolve Medical is offering no-cost, 60-day pilots to health plans, pharmacy benefit managers, health systems, and pharmacy chains. Pilots run on Resolve Medical’s infrastructure and require no software installation or IT integration from the participating organization.

About Resolve Medical, LLC

Resolve Medical, LLC is a Cleveland, Ohio health technology company focused on medication safety and polypharmacy risk. Its IntractMD™ platform serves patients, health plans, health systems, and pharmacies through three connected surfaces: a patient-facing interaction checker, a proactive supplement screening tool, and a clinical workflow for pharmacists conducting medication reviews.

Media Contact
Tom Lash, Founder · Resolve Medical, LLC
216-509-0672 · info@resolve.med
700 W Saint Clair Ave., Suite 100, Cleveland, OH 44113

IntractMD™ is a trademark of Resolve Medical, LLC. Patent pending. IntractMD is intended for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment.

Ready to see IntractMD in action?

Try the patient app free — no account required. Or contact us to schedule a 60-day pilot for your health plan or MTM program.

Launch IntractMD Free → info@resolve.med · 216-509-0672